{"source":{"id":12380,"identifier":"5297","identifier_type":"int","name":"PI4KA","properties":{"url":"http://identifiers.org/ncbigene/5297","source":"Entrez Gene","license":"CC0 1.0","chromosome":"22","description":"phosphatidylinositol 4-kinase, catalytic, alpha"},"metanode":"Gene"},"target":{"id":24934,"identifier":"805","identifier_type":"int","name":"CALM2","properties":{"url":"http://identifiers.org/ncbigene/805","source":"Entrez Gene","license":"CC0 1.0","chromosome":"2","description":"calmodulin 2 (phosphorylase kinase, delta)"},"metanode":"Gene"},"path_counts":[{"id":143421614,"adjusted_p_value":2.130726662331869e-09,"path_count":5614,"dwpc":3.331367151476209,"p_value":1.0707169157446579e-11,"reversed":false,"metapath_abbreviation":"GeAeGiG","metapath_name":"Gene–expresses–Anatomy–expresses–Gene–interacts–Gene","metapath_length":3,"metapath_path_count_density":0.621691,"metapath_path_count_mean":225.803,"metapath_path_count_max":316362,"metapath_dwpc_raw_mean":1.7866400000000002e-05,"metapath_n_similar":199,"metapath_p_threshold":6.419019708424056e-05,"metapath_id":"GeAeGiG","metapath_reversed":false,"metapath_metaedges":[["Gene","Anatomy","expresses","both"],["Anatomy","Gene","expresses","both"],["Gene","Gene","interacts","both"]],"dgp_id":32182341,"dgp_source_degree":29,"dgp_target_degree":314,"dgp_n_dwpcs":55200,"dgp_n_nonzero_dwpcs":55200,"dgp_nonzero_mean":3.0496288395998636,"dgp_nonzero_sd":0.0408723606643956,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Gene)-[:EXPRESSES_AeG]-(n1)-[:EXPRESSES_AeG]-(n2)-[:INTERACTS_GiG]-(n3:Gene)\nUSING JOIN ON n1\nWHERE n0.identifier = 5297 // PI4KA\nAND n3.identifier = 805 // CALM2\nAND n0 <> n2 AND n0 <> n3 AND n2 <> n3\nWITH\n[\nsize((n0)-[:EXPRESSES_AeG]-()),\nsize(()-[:EXPRESSES_AeG]-(n1)),\nsize((n1)-[:EXPRESSES_AeG]-()),\nsize(()-[:EXPRESSES_AeG]-(n2)),\nsize((n2)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n  path AS neo4j_path,\n  substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n  PDP,\n  100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":40944835,"adjusted_p_value":0.009828145363027322,"path_count":330,"dwpc":3.390960571891475,"p_value":4.9387665140840816e-05,"reversed":false,"metapath_abbreviation":"GdAdGiG","metapath_name":"Gene–downregulates–Anatomy–downregulates–Gene–interacts–Gene","metapath_length":3,"metapath_path_count_density":0.470102,"metapath_path_count_mean":14.3967,"metapath_path_count_max":43673,"metapath_dwpc_raw_mean":1.4451900000000001e-05,"metapath_n_similar":199,"metapath_p_threshold":6.419019708424056e-05,"metapath_id":"GdAdGiG","metapath_reversed":false,"metapath_metaedges":[["Gene","Anatomy","downregulates","both"],["Anatomy","Gene","downregulates","both"],["Gene","Gene","interacts","both"]],"dgp_id":31348845,"dgp_source_degree":5,"dgp_target_degree":314,"dgp_n_dwpcs":281200,"dgp_n_nonzero_dwpcs":281200,"dgp_nonzero_mean":3.0587914886301975,"dgp_nonzero_sd":0.08259507746588904,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Gene)-[:DOWNREGULATES_AdG]-(n1)-[:DOWNREGULATES_AdG]-(n2)-[:INTERACTS_GiG]-(n3:Gene)\nUSING JOIN ON n1\nWHERE n0.identifier = 5297 // PI4KA\nAND n3.identifier = 805 // CALM2\nAND n0 <> n2 AND n0 <> n3 AND n2 <> n3\nWITH\n[\nsize((n0)-[:DOWNREGULATES_AdG]-()),\nsize(()-[:DOWNREGULATES_AdG]-(n1)),\nsize((n1)-[:DOWNREGULATES_AdG]-()),\nsize(()-[:DOWNREGULATES_AdG]-(n2)),\nsize((n2)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n  path AS neo4j_path,\n  substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n  PDP,\n  100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"}],"n_metapaths":2,"pathcount_table_random_id":40944835,"pathcount_table_max_id":169602979}