{"source":{"id":17054,"identifier":"DB00331","identifier_type":"str","name":"Metformin","properties":{"url":"http://www.drugbank.ca/drugs/DB00331","inchi":"InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)","source":"DrugBank","license":"CC BY-NC 4.0","inchikey":"InChIKey=XZWYZXLIPXDOLR-UHFFFAOYSA-N"},"metanode":"Compound"},"target":{"id":6602,"identifier":"DOID:1612","identifier_type":"str","name":"breast cancer","properties":{"url":"http://purl.obolibrary.org/obo/DOID_1612","source":"Disease Ontology","license":"CC BY 3.0"},"metanode":"Disease"},"path_counts":[{"id":77513331,"adjusted_p_value":0.003951112689446279,"path_count":484,"dwpc":3.5346993748913973,"p_value":3.2653823879721316e-05,"reversed":false,"metapath_abbreviation":"CbGeAlD","metapath_name":"Compound–binds–Gene–expresses–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.800046,"metapath_path_count_mean":17.3173,"metapath_path_count_max":1670,"metapath_dwpc_raw_mean":0.000259132,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGeAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Anatomy","expresses","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":21810569,"dgp_source_degree":56,"dgp_target_degree":39,"dgp_n_dwpcs":800,"dgp_n_nonzero_dwpcs":800,"dgp_nonzero_mean":1.9215512456202535,"dgp_nonzero_sd":0.33090308109283123,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:EXPRESSES_AeG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:EXPRESSES_AeG]-()),\nsize(()-[:EXPRESSES_AeG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":26911811,"adjusted_p_value":0.034321317684374276,"path_count":14,"dwpc":4.563918531032985,"p_value":0.00028364725358987007,"reversed":false,"metapath_abbreviation":"CtDlAlD","metapath_name":"Compound–treats–Disease–localizes–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.18212,"metapath_path_count_mean":1.29946,"metapath_path_count_max":279,"metapath_dwpc_raw_mean":0.000563455,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDlAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Anatomy","localizes","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":23793754,"dgp_source_degree":3,"dgp_target_degree":39,"dgp_n_dwpcs":15200,"dgp_n_nonzero_dwpcs":15194,"dgp_nonzero_mean":2.552159071387449,"dgp_nonzero_sd":0.48489767303472786,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:LOCALIZES_DlA]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":72430549,"adjusted_p_value":0.045993636486382335,"path_count":126,"dwpc":4.386227813718969,"p_value":0.0003801126982345647,"reversed":false,"metapath_abbreviation":"CbGdAlD","metapath_name":"Compound–binds–Gene–downregulates–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.590437,"metapath_path_count_mean":4.04788,"metapath_path_count_max":372,"metapath_dwpc_raw_mean":0.000121205,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGdAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Anatomy","downregulates","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":21763190,"dgp_source_degree":56,"dgp_target_degree":39,"dgp_n_dwpcs":800,"dgp_n_nonzero_dwpcs":791,"dgp_nonzero_mean":2.1106664913501048,"dgp_nonzero_sd":0.5350022943256412,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:DOWNREGULATES_AdG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:DOWNREGULATES_AdG]-()),\nsize(()-[:DOWNREGULATES_AdG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":113108500,"adjusted_p_value":0.04698025324807386,"path_count":42,"dwpc":4.140063444985263,"p_value":0.00038826655576920546,"reversed":false,"metapath_abbreviation":"CbGiGaD","metapath_name":"Compound–binds–Gene–interacts–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.348183,"metapath_path_count_mean":2.23582,"metapath_path_count_max":809,"metapath_dwpc_raw_mean":0.00019613400000000002,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGiGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","interacts","both"],["Gene","Disease","associates","both"]],"dgp_id":21828791,"dgp_source_degree":56,"dgp_target_degree":540,"dgp_n_dwpcs":200,"dgp_n_nonzero_dwpcs":200,"dgp_nonzero_mean":2.686698590200101,"dgp_nonzero_sd":0.37751699541244615,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:INTERACTS_GiG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":67500273,"adjusted_p_value":0.10051956724479168,"path_count":163,"dwpc":4.699608393014548,"p_value":0.0008307402251635675,"reversed":false,"metapath_abbreviation":"CbGr>GaD","metapath_name":"Compound–binds–Gene→regulates→Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.32456799999999997,"metapath_path_count_mean":1.8491900000000001,"metapath_path_count_max":755,"metapath_dwpc_raw_mean":7.56952e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGr>GaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","associates","both"]],"dgp_id":21960830,"dgp_source_degree":56,"dgp_target_degree":540,"dgp_n_dwpcs":200,"dgp_n_nonzero_dwpcs":200,"dgp_nonzero_mean":3.2657197245645078,"dgp_nonzero_sd":0.40759580920134286,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:REGULATES_GrG]->(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":142020565,"adjusted_p_value":0.1005235732343783,"path_count":103,"dwpc":5.097303896409291,"p_value":0.0008307733325155232,"reversed":false,"metapath_abbreviation":"CbGr>GuD","metapath_name":"Compound–binds–Gene→regulates→Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.146992,"metapath_path_count_mean":1.0096100000000001,"metapath_path_count_max":526,"metapath_dwpc_raw_mean":5.89699e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGr>GuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","upregulates","both"]],"dgp_id":22043084,"dgp_source_degree":56,"dgp_target_degree":250,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":5400,"dgp_nonzero_mean":3.501803136530045,"dgp_nonzero_sd":0.4518997502518118,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:REGULATES_GrG]->(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":114205387,"adjusted_p_value":0.1248117671211756,"path_count":59,"dwpc":4.921895497900556,"p_value":0.0010315022076130215,"reversed":false,"metapath_abbreviation":"CbG n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":112488887,"adjusted_p_value":0.3013641844647006,"path_count":16,"dwpc":5.390652904661932,"p_value":0.0024906130947495914,"reversed":false,"metapath_abbreviation":"CtDaGuD","metapath_name":"Compound–treats–Disease–associates–Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0567904,"metapath_path_count_mean":0.570303,"metapath_path_count_max":159,"metapath_dwpc_raw_mean":0.0001389,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDaGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","associates","both"],["Gene","Disease","upregulates","both"]],"dgp_id":23755239,"dgp_source_degree":3,"dgp_target_degree":250,"dgp_n_dwpcs":102600,"dgp_n_nonzero_dwpcs":102339,"dgp_nonzero_mean":3.7252708618200967,"dgp_nonzero_sd":0.5311944537003014,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:ASSOCIATES_DaG]-(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":678248,"adjusted_p_value":0.653270938930521,"path_count":99,"dwpc":4.140174738675961,"p_value":0.005398933379591082,"reversed":false,"metapath_abbreviation":"CtDaGaD","metapath_name":"Compound–treats–Disease–associates–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.193196,"metapath_path_count_mean":4.464180000000001,"metapath_path_count_max":876,"metapath_dwpc_raw_mean":0.000403948,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDaGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","associates","both"],["Gene","Disease","associates","both"]],"dgp_id":23724358,"dgp_source_degree":3,"dgp_target_degree":540,"dgp_n_dwpcs":3800,"dgp_n_nonzero_dwpcs":3800,"dgp_nonzero_mean":3.2800660008843163,"dgp_nonzero_sd":0.31563132652903,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:ASSOCIATES_DaG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":96988112,"adjusted_p_value":1.0,"path_count":512,"dwpc":3.089869181245992,"p_value":0.009034196756478506,"reversed":false,"metapath_abbreviation":"CdG n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":10892498,"adjusted_p_value":1.0,"path_count":21,"dwpc":5.071665342675126,"p_value":0.013791674143867196,"reversed":false,"metapath_abbreviation":"CtDaGdD","metapath_name":"Compound–treats–Disease–associates–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.055718100000000007,"metapath_path_count_mean":0.44149799999999995,"metapath_path_count_max":109,"metapath_dwpc_raw_mean":0.000124723,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDaGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","associates","both"],["Gene","Disease","downregulates","both"]],"dgp_id":23731785,"dgp_source_degree":3,"dgp_target_degree":250,"dgp_n_dwpcs":98800,"dgp_n_nonzero_dwpcs":98160,"dgp_nonzero_mean":3.690298347018518,"dgp_nonzero_sd":0.5762794425175636,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:ASSOCIATES_DaG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":48876787,"adjusted_p_value":1.0,"path_count":3,"dwpc":4.070490832162907,"p_value":0.016564731132729372,"reversed":false,"metapath_abbreviation":"CbGdDrD","metapath_name":"Compound–binds–Gene–downregulates–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.135798,"metapath_path_count_mean":0.221795,"metapath_path_count_max":19,"metapath_dwpc_raw_mean":9.828280000000001e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGdDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Disease","downregulates","both"],["Disease","Disease","resembles","both"]],"dgp_id":21801239,"dgp_source_degree":56,"dgp_target_degree":3,"dgp_n_dwpcs":2800,"dgp_n_nonzero_dwpcs":812,"dgp_nonzero_mean":2.2979944741830063,"dgp_nonzero_sd":1.0081734776406486,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:DOWNREGULATES_DdG]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n2 <> n3\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":167522760,"adjusted_p_value":1.0,"path_count":90,"dwpc":4.020134446208101,"p_value":0.017607793196850408,"reversed":false,"metapath_abbreviation":"CuGr>GuD","metapath_name":"Compound–upregulates–Gene→regulates→Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.10528900000000001,"metapath_path_count_mean":4.58855,"metapath_path_count_max":1129,"metapath_dwpc_raw_mean":8.77319e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGr>GuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","upregulates","both"]],"dgp_id":24772971,"dgp_source_degree":8,"dgp_target_degree":250,"dgp_n_dwpcs":145800,"dgp_n_nonzero_dwpcs":145621,"dgp_nonzero_mean":2.4665584981776765,"dgp_nonzero_sd":0.6488129682333391,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:REGULATES_GrG]->(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":167154176,"adjusted_p_value":1.0,"path_count":1,"dwpc":6.475597896851278,"p_value":0.01837763565445217,"reversed":false,"metapath_abbreviation":"CtDpCpD","metapath_name":"Compound–treats–Disease–palliates–Compound–palliates–Disease","metapath_length":3,"metapath_path_count_density":0.00812232,"metapath_path_count_mean":0.021248799999999998,"metapath_path_count_max":31,"metapath_dwpc_raw_mean":0.00010631,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDpCpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Compound","palliates","both"],["Compound","Disease","palliates","both"]],"dgp_id":23804058,"dgp_source_degree":3,"dgp_target_degree":14,"dgp_n_dwpcs":7600,"dgp_n_nonzero_dwpcs":3345,"dgp_nonzero_mean":4.210930443126998,"dgp_nonzero_sd":1.1903616501345484,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:PALLIATES_CpD]-(n2)-[:PALLIATES_CpD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2 AND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n2)),\nsize((n2)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":112893663,"adjusted_p_value":1.0,"path_count":7,"dwpc":5.418669178433626,"p_value":0.019138619393998163,"reversed":false,"metapath_abbreviation":"CtDdGdD","metapath_name":"Compound–treats–Disease–downregulates–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0313934,"metapath_path_count_mean":0.241022,"metapath_path_count_max":123,"metapath_dwpc_raw_mean":6.82525e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDdGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","downregulates","both"],["Gene","Disease","downregulates","both"]],"dgp_id":23767659,"dgp_source_degree":3,"dgp_target_degree":250,"dgp_n_dwpcs":98800,"dgp_n_nonzero_dwpcs":84060,"dgp_nonzero_mean":3.6635602586740057,"dgp_nonzero_sd":0.7927141924002727,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:DOWNREGULATES_DdG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":15113069,"adjusted_p_value":1.0,"path_count":117,"dwpc":3.4991699833130117,"p_value":0.023317287337446795,"reversed":false,"metapath_abbreviation":"CuGr>GaD","metapath_name":"Compound–upregulates–Gene→regulates→Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.261612,"metapath_path_count_mean":8.08893,"metapath_path_count_max":1529,"metapath_dwpc_raw_mean":0.000111195,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGr>GaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","associates","both"]],"dgp_id":24632918,"dgp_source_degree":8,"dgp_target_degree":540,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":5399,"dgp_nonzero_mean":2.3121920739351287,"dgp_nonzero_sd":0.5373848327056929,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:REGULATES_GrG]->(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":97531640,"adjusted_p_value":1.0,"path_count":1,"dwpc":3.8332261091694466,"p_value":0.02448539719597531,"reversed":false,"metapath_abbreviation":"CtDrDrD","metapath_name":"Compound–treats–Disease–resembles–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.055972,"metapath_path_count_mean":0.28526399999999996,"metapath_path_count_max":144,"metapath_dwpc_raw_mean":0.000430315,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDrDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Disease","resembles","both"],["Disease","Disease","resembles","both"]],"dgp_id":23808511,"dgp_source_degree":3,"dgp_target_degree":3,"dgp_n_dwpcs":53200,"dgp_n_nonzero_dwpcs":30074,"dgp_nonzero_mean":2.517955090636328,"dgp_nonzero_sd":0.7006119113977642,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:RESEMBLES_DrD]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2 AND n1 <> n3 AND n2 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":167119847,"adjusted_p_value":1.0,"path_count":86,"dwpc":3.480260005364498,"p_value":0.02961801201131862,"reversed":false,"metapath_abbreviation":"CdGdCtD","metapath_name":"Compound–downregulates–Gene–downregulates–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.17690899999999998,"metapath_path_count_mean":4.51441,"metapath_path_count_max":1651,"metapath_dwpc_raw_mean":0.000341563,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGdCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Compound","downregulates","both"],["Compound","Disease","treats","both"]],"dgp_id":22773547,"dgp_source_degree":22,"dgp_target_degree":29,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":1200,"dgp_nonzero_mean":2.73636530998999,"dgp_nonzero_sd":0.372141580199267,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:DOWNREGULATES_CdG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":73961466,"adjusted_p_value":1.0,"path_count":5,"dwpc":5.188576435472119,"p_value":0.031145617104940834,"reversed":false,"metapath_abbreviation":"CtDuGdD","metapath_name":"Compound–treats–Disease–upregulates–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0302882,"metapath_path_count_mean":0.139354,"metapath_path_count_max":59,"metapath_dwpc_raw_mean":8.325969999999999e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDuGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","upregulates","both"],["Gene","Disease","downregulates","both"]],"dgp_id":23832603,"dgp_source_degree":3,"dgp_target_degree":250,"dgp_n_dwpcs":98800,"dgp_n_nonzero_dwpcs":80129,"dgp_nonzero_mean":3.6899331737695023,"dgp_nonzero_sd":0.7840126846658535,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:UPREGULATES_DuG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":142552339,"adjusted_p_value":1.0,"path_count":13,"dwpc":4.6019606799462744,"p_value":0.03989373143005087,"reversed":false,"metapath_abbreviation":"CbG n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":51026471,"adjusted_p_value":1.0,"path_count":100,"dwpc":3.368403036173284,"p_value":0.041419841119016906,"reversed":false,"metapath_abbreviation":"CuGiGaD","metapath_name":"Compound–upregulates–Gene–interacts–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.23424899999999999,"metapath_path_count_mean":5.42903,"metapath_path_count_max":1114,"metapath_dwpc_raw_mean":0.000138883,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGiGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Gene","interacts","both"],["Gene","Disease","associates","both"]],"dgp_id":24402806,"dgp_source_degree":8,"dgp_target_degree":540,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":5390,"dgp_nonzero_mean":2.1110526346677996,"dgp_nonzero_sd":0.6544400882432083,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:INTERACTS_GiG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":117620294,"adjusted_p_value":1.0,"path_count":5,"dwpc":4.255349947963811,"p_value":0.04278717173688437,"reversed":false,"metapath_abbreviation":"CdGcGaD","metapath_name":"Compound–downregulates–Gene–covaries–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.0824883,"metapath_path_count_mean":0.291049,"metapath_path_count_max":68,"metapath_dwpc_raw_mean":4.7755e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGcGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","covaries","both"],["Gene","Disease","associates","both"]],"dgp_id":22557200,"dgp_source_degree":22,"dgp_target_degree":540,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":1061,"dgp_nonzero_mean":2.4442059675365,"dgp_nonzero_sd":0.9731386488165376,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:COVARIES_GcG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:COVARIES_GcG]-()),\nsize(()-[:COVARIES_GcG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":128191287,"adjusted_p_value":1.0,"path_count":14,"dwpc":4.585979496774474,"p_value":0.04822840626688617,"reversed":false,"metapath_abbreviation":"CbG n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":333993,"adjusted_p_value":1.0,"path_count":25,"dwpc":4.05177679704909,"p_value":0.04904336728138025,"reversed":false,"metapath_abbreviation":"CuGiGdD","metapath_name":"Compound–upregulates–Gene–interacts–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0794924,"metapath_path_count_mean":1.44274,"metapath_path_count_max":315,"metapath_dwpc_raw_mean":6.63879e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGiGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Gene","interacts","both"],["Gene","Disease","downregulates","both"]],"dgp_id":24429213,"dgp_source_degree":8,"dgp_target_degree":250,"dgp_n_dwpcs":140400,"dgp_n_nonzero_dwpcs":131603,"dgp_nonzero_mean":2.415469444970876,"dgp_nonzero_sd":0.9097945399183445,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:INTERACTS_GiG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":97958430,"adjusted_p_value":1.0,"path_count":3,"dwpc":4.934129306471353,"p_value":0.056586229771279854,"reversed":false,"metapath_abbreviation":"CtDdGuD","metapath_name":"Compound–treats–Disease–downregulates–Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.028566900000000003,"metapath_path_count_mean":0.143733,"metapath_path_count_max":70,"metapath_dwpc_raw_mean":8.00549e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDdGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","downregulates","both"],["Gene","Disease","upregulates","both"]],"dgp_id":23791113,"dgp_source_degree":3,"dgp_target_degree":250,"dgp_n_dwpcs":102600,"dgp_n_nonzero_dwpcs":82840,"dgp_nonzero_mean":3.708172897358525,"dgp_nonzero_sd":0.7911141310816485,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:DOWNREGULATES_DdG]-(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":51600505,"adjusted_p_value":1.0,"path_count":7,"dwpc":3.3844578774229146,"p_value":0.05921053603971112,"reversed":false,"metapath_abbreviation":"CtDpSpD","metapath_name":"Compound–treats–Disease–presents–Symptom–presents–Disease","metapath_length":3,"metapath_path_count_density":0.181701,"metapath_path_count_mean":1.43773,"metapath_path_count_max":297,"metapath_dwpc_raw_mean":0.000537409,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDpSpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Symptom","presents","both"],["Symptom","Disease","presents","both"]],"dgp_id":23806197,"dgp_source_degree":3,"dgp_target_degree":34,"dgp_n_dwpcs":15200,"dgp_n_nonzero_dwpcs":15197,"dgp_nonzero_mean":2.508896042956027,"dgp_nonzero_sd":0.5295295813881706,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:PRESENTS_DpS]-(n2)-[:PRESENTS_DpS]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:PRESENTS_DpS]-()),\nsize(()-[:PRESENTS_DpS]-(n2)),\nsize((n2)-[:PRESENTS_DpS]-()),\nsize(()-[:PRESENTS_DpS]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":50670435,"adjusted_p_value":1.0,"path_count":1,"dwpc":2.3928704143429207,"p_value":0.061041853515744426,"reversed":false,"metapath_abbreviation":"CuGdDrD","metapath_name":"Compound–upregulates–Gene–downregulates–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.104146,"metapath_path_count_mean":0.431654,"metapath_path_count_max":82,"metapath_dwpc_raw_mean":0.000103826,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGdDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Disease","downregulates","both"],["Disease","Disease","resembles","both"]],"dgp_id":24357165,"dgp_source_degree":8,"dgp_target_degree":3,"dgp_n_dwpcs":75600,"dgp_n_nonzero_dwpcs":6398,"dgp_nonzero_mean":2.8647348775578405,"dgp_nonzero_sd":0.742271377546388,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:DOWNREGULATES_DdG]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n2 <> n3\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":168738058,"adjusted_p_value":1.0,"path_count":28,"dwpc":3.1851014648233953,"p_value":0.06353826772564779,"reversed":false,"metapath_abbreviation":"CuGuCtD","metapath_name":"Compound–upregulates–Gene–upregulates–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.148356,"metapath_path_count_mean":2.92613,"metapath_path_count_max":1209,"metapath_dwpc_raw_mean":0.000310118,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGuCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Compound","upregulates","both"],["Compound","Disease","treats","both"]],"dgp_id":24842591,"dgp_source_degree":8,"dgp_target_degree":29,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":5397,"dgp_nonzero_mean":2.202899800153523,"dgp_nonzero_sd":0.6021415430197289,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:UPREGULATES_CuG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":106228526,"adjusted_p_value":1.0,"path_count":27,"dwpc":3.5570771307610203,"p_value":0.06723033943632191,"reversed":false,"metapath_abbreviation":"CuGr>GdD","metapath_name":"Compound–upregulates–Gene→regulates→Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.100356,"metapath_path_count_mean":3.3594199999999996,"metapath_path_count_max":516,"metapath_dwpc_raw_mean":7.62999e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGr>GdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","downregulates","both"]],"dgp_id":24659325,"dgp_source_degree":8,"dgp_target_degree":250,"dgp_n_dwpcs":140400,"dgp_n_nonzero_dwpcs":139901,"dgp_nonzero_mean":2.4296323563709636,"dgp_nonzero_sd":0.7058168339413708,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:REGULATES_GrG]->(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":132731078,"adjusted_p_value":1.0,"path_count":144,"dwpc":2.7594640937243136,"p_value":0.06901256130115166,"reversed":false,"metapath_abbreviation":"CuG n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":51714672,"adjusted_p_value":1.0,"path_count":1,"dwpc":3.654587805413775,"p_value":0.07636997413702667,"reversed":false,"metapath_abbreviation":"CdGbCtD","metapath_name":"Compound–downregulates–Gene–binds–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.025434599999999998,"metapath_path_count_mean":0.08076230000000001,"metapath_path_count_max":42,"metapath_dwpc_raw_mean":3.85005e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGbCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Compound","binds","both"],["Compound","Disease","treats","both"]],"dgp_id":22525597,"dgp_source_degree":22,"dgp_target_degree":29,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":288,"dgp_nonzero_mean":3.2494598868343867,"dgp_nonzero_sd":1.0707393905520752,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:BINDS_CbG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":126627871,"adjusted_p_value":1.0,"path_count":25,"dwpc":2.6019552338863337,"p_value":0.07665678971694347,"reversed":false,"metapath_abbreviation":"CdGdAlD","metapath_name":"Compound–downregulates–Gene–downregulates–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.319762,"metapath_path_count_mean":7.40641,"metapath_path_count_max":945,"metapath_dwpc_raw_mean":9.026700000000001e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGdAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Anatomy","downregulates","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":22720175,"dgp_source_degree":22,"dgp_target_degree":39,"dgp_n_dwpcs":4800,"dgp_n_nonzero_dwpcs":4732,"dgp_nonzero_mean":1.7575179531740346,"dgp_nonzero_sd":0.5599656729038113,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:DOWNREGULATES_AdG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:DOWNREGULATES_AdG]-()),\nsize(()-[:DOWNREGULATES_AdG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":20791062,"adjusted_p_value":1.0,"path_count":85,"dwpc":3.447797409851131,"p_value":0.0856786500783511,"reversed":false,"metapath_abbreviation":"CdGr>GuD","metapath_name":"Compound–downregulates–Gene→regulates→Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.115462,"metapath_path_count_mean":5.24488,"metapath_path_count_max":1107,"metapath_dwpc_raw_mean":9.533129999999999e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGr>GuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","upregulates","both"]],"dgp_id":23203499,"dgp_source_degree":22,"dgp_target_degree":250,"dgp_n_dwpcs":32400,"dgp_n_nonzero_dwpcs":32400,"dgp_nonzero_mean":2.885580043810075,"dgp_nonzero_sd":0.40033663152163457,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:REGULATES_GrG]->(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":4269517,"adjusted_p_value":1.0,"path_count":134,"dwpc":3.1776015317859327,"p_value":0.08635278747636652,"reversed":false,"metapath_abbreviation":"CdGr>GaD","metapath_name":"Compound–downregulates–Gene→regulates→Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.29232800000000003,"metapath_path_count_mean":9.07357,"metapath_path_count_max":1393,"metapath_dwpc_raw_mean":0.00011774700000000001,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGr>GaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","associates","both"]],"dgp_id":23062010,"dgp_source_degree":22,"dgp_target_degree":540,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":1200,"dgp_nonzero_mean":2.7050547748859497,"dgp_nonzero_sd":0.3384201984272396,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:REGULATES_GrG]->(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":98054384,"adjusted_p_value":1.0,"path_count":4,"dwpc":3.2308571218969195,"p_value":0.09191255105717275,"reversed":false,"metapath_abbreviation":"CuGuCpD","metapath_name":"Compound–upregulates–Gene–upregulates–Compound–palliates–Disease","metapath_length":3,"metapath_path_count_density":0.0656135,"metapath_path_count_mean":0.5202140000000001,"metapath_path_count_max":303,"metapath_dwpc_raw_mean":0.000135634,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGuCpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Compound","upregulates","both"],["Compound","Disease","palliates","both"]],"dgp_id":24840575,"dgp_source_degree":8,"dgp_target_degree":14,"dgp_n_dwpcs":10800,"dgp_n_nonzero_dwpcs":7843,"dgp_nonzero_mean":2.176696644105656,"dgp_nonzero_sd":0.9136133445678573,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:UPREGULATES_CuG]-(n2)-[:PALLIATES_CpD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n2)),\nsize((n2)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":142515870,"adjusted_p_value":1.0,"path_count":18,"dwpc":3.6336547322859323,"p_value":0.09329130704265634,"reversed":false,"metapath_abbreviation":"CdGuCtD","metapath_name":"Compound–downregulates–Gene–upregulates–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.0889599,"metapath_path_count_mean":0.837563,"metapath_path_count_max":321,"metapath_dwpc_raw_mean":0.000136586,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGuCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Compound","upregulates","both"],["Compound","Disease","treats","both"]],"dgp_id":23270257,"dgp_source_degree":22,"dgp_target_degree":29,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":1183,"dgp_nonzero_mean":2.5112520337865583,"dgp_nonzero_sd":0.8188444755623576,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:UPREGULATES_CuG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":98339282,"adjusted_p_value":1.0,"path_count":36,"dwpc":4.148527682259019,"p_value":0.09651902561245157,"reversed":false,"metapath_abbreviation":"CbGr>GdD","metapath_name":"Compound–binds–Gene→regulates→Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.138244,"metapath_path_count_mean":0.758997,"metapath_path_count_max":256,"metapath_dwpc_raw_mean":5.0237799999999995e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGr>GdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","downregulates","both"]],"dgp_id":21976631,"dgp_source_degree":56,"dgp_target_degree":250,"dgp_n_dwpcs":5200,"dgp_n_nonzero_dwpcs":5200,"dgp_nonzero_mean":3.4973056056969827,"dgp_nonzero_sd":0.4895431979920396,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:REGULATES_GrG]->(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":106995726,"adjusted_p_value":1.0,"path_count":2,"dwpc":2.2208486272592425,"p_value":0.09746749157070841,"reversed":false,"metapath_abbreviation":"CdGuDrD","metapath_name":"Compound–downregulates–Gene–upregulates–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.125959,"metapath_path_count_mean":0.625508,"metapath_path_count_max":79,"metapath_dwpc_raw_mean":0.000116155,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGuDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Disease","upregulates","both"],["Disease","Disease","resembles","both"]],"dgp_id":23285651,"dgp_source_degree":22,"dgp_target_degree":3,"dgp_n_dwpcs":16800,"dgp_n_nonzero_dwpcs":4208,"dgp_nonzero_mean":2.093911119617837,"dgp_nonzero_sd":0.8484643387829551,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:UPREGULATES_DuG]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n2 <> n3\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":141417483,"adjusted_p_value":1.0,"path_count":3,"dwpc":3.252331054134336,"p_value":0.0975771845917332,"reversed":false,"metapath_abbreviation":"CuGdCtD","metapath_name":"Compound–upregulates–Gene–downregulates–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.0854936,"metapath_path_count_mean":1.00547,"metapath_path_count_max":387,"metapath_dwpc_raw_mean":0.000139589,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGdCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Compound","downregulates","both"],["Compound","Disease","treats","both"]],"dgp_id":24341101,"dgp_source_degree":8,"dgp_target_degree":29,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":4723,"dgp_nonzero_mean":2.066805145380311,"dgp_nonzero_sd":0.9462586620512786,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:DOWNREGULATES_CdG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":27252246,"adjusted_p_value":1.0,"path_count":1,"dwpc":4.069441046819882,"p_value":0.1007583684652619,"reversed":false,"metapath_abbreviation":"CuGuD","metapath_name":"Compound–upregulates–Gene–upregulates–Disease","metapath_length":2,"metapath_path_count_density":0.0262717,"metapath_path_count_mean":0.06692569999999999,"metapath_path_count_max":22,"metapath_dwpc_raw_mean":0.000135124,"metapath_n_similar":13,"metapath_p_threshold":1.0,"metapath_id":"CuGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Disease","upregulates","both"]],"dgp_id":4124216,"dgp_source_degree":8,"dgp_target_degree":250,"dgp_n_dwpcs":145800,"dgp_n_nonzero_dwpcs":26669,"dgp_nonzero_mean":4.183802261684422,"dgp_nonzero_sd":0.6438989025236784,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:UPREGULATES_DuG]-(n2:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n2.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n2))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":112967029,"adjusted_p_value":1.0,"path_count":1,"dwpc":2.169914922408736,"p_value":0.109664276566758,"reversed":false,"metapath_abbreviation":"CbGaDrD","metapath_name":"Compound–binds–Gene–associates–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.410128,"metapath_path_count_mean":1.46755,"metapath_path_count_max":59,"metapath_dwpc_raw_mean":0.00044245199999999997,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGaDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Disease","associates","both"],["Disease","Disease","resembles","both"]],"dgp_id":21620954,"dgp_source_degree":56,"dgp_target_degree":3,"dgp_n_dwpcs":2800,"dgp_n_nonzero_dwpcs":2508,"dgp_nonzero_mean":1.2949397042821509,"dgp_nonzero_sd":0.7478259649977236,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:ASSOCIATES_DaG]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n2 <> n3\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":128214864,"adjusted_p_value":1.0,"path_count":35,"dwpc":2.3764149601937445,"p_value":0.11940455530163151,"reversed":false,"metapath_abbreviation":"CdGuAlD","metapath_name":"Compound–downregulates–Gene–upregulates–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.317575,"metapath_path_count_mean":7.33656,"metapath_path_count_max":690,"metapath_dwpc_raw_mean":0.00010222600000000001,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGuAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Anatomy","upregulates","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":23216885,"dgp_source_degree":22,"dgp_target_degree":39,"dgp_n_dwpcs":4800,"dgp_n_nonzero_dwpcs":4738,"dgp_nonzero_mean":1.7284541892784524,"dgp_nonzero_sd":0.5441426925484705,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:UPREGULATES_AuG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:UPREGULATES_AuG]-()),\nsize(()-[:UPREGULATES_AuG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":47594528,"adjusted_p_value":1.0,"path_count":1,"dwpc":1.6357682430587739,"p_value":0.11982495003093771,"reversed":false,"metapath_abbreviation":"CuGaDrD","metapath_name":"Compound–upregulates–Gene–associates–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.178484,"metapath_path_count_mean":1.17964,"metapath_path_count_max":112,"metapath_dwpc_raw_mean":0.00018600799999999998,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGaDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Disease","associates","both"],["Disease","Disease","resembles","both"]],"dgp_id":24038129,"dgp_source_degree":8,"dgp_target_degree":3,"dgp_n_dwpcs":75600,"dgp_n_nonzero_dwpcs":17893,"dgp_nonzero_mean":1.78641790772731,"dgp_nonzero_sd":0.8656172759174137,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:ASSOCIATES_DaG]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n2 <> n3\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":64864711,"adjusted_p_value":1.0,"path_count":230,"dwpc":2.279945188763921,"p_value":0.1319402342911689,"reversed":false,"metapath_abbreviation":"CdGeAlD","metapath_name":"Compound–downregulates–Gene–expresses–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.44580600000000004,"metapath_path_count_mean":51.614,"metapath_path_count_max":4247,"metapath_dwpc_raw_mean":0.000181137,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGeAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Anatomy","expresses","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":22803785,"dgp_source_degree":22,"dgp_target_degree":39,"dgp_n_dwpcs":4800,"dgp_n_nonzero_dwpcs":4800,"dgp_nonzero_mean":1.8900053433921868,"dgp_nonzero_sd":0.3461661191449261,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:EXPRESSES_AeG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:EXPRESSES_AeG]-()),\nsize(()-[:EXPRESSES_AeG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":73879,"adjusted_p_value":1.0,"path_count":14,"dwpc":2.01776356103161,"p_value":0.13670783137847875,"reversed":false,"metapath_abbreviation":"CuGuAlD","metapath_name":"Compound–upregulates–Gene–upregulates–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.30537,"metapath_path_count_mean":7.793880000000001,"metapath_path_count_max":777,"metapath_dwpc_raw_mean":0.00011132,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGuAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Anatomy","upregulates","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":24786427,"dgp_source_degree":8,"dgp_target_degree":39,"dgp_n_dwpcs":21600,"dgp_n_nonzero_dwpcs":21130,"dgp_nonzero_mean":1.400384079226118,"dgp_nonzero_sd":0.5740793704418491,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:UPREGULATES_AuG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:UPREGULATES_AuG]-()),\nsize(()-[:UPREGULATES_AuG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":112227249,"adjusted_p_value":1.0,"path_count":10,"dwpc":3.2187553611741118,"p_value":0.1560923088085931,"reversed":false,"metapath_abbreviation":"CdGdCpD","metapath_name":"Compound–downregulates–Gene–downregulates–Compound–palliates–Disease","metapath_length":3,"metapath_path_count_density":0.0834948,"metapath_path_count_mean":0.7409979999999999,"metapath_path_count_max":274,"metapath_dwpc_raw_mean":0.000159982,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGdCpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Compound","downregulates","both"],["Compound","Disease","palliates","both"]],"dgp_id":22771559,"dgp_source_degree":22,"dgp_target_degree":14,"dgp_n_dwpcs":2400,"dgp_n_nonzero_dwpcs":2306,"dgp_nonzero_mean":2.4727680216941046,"dgp_nonzero_sd":0.7728072706112241,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:DOWNREGULATES_CdG]-(n2)-[:PALLIATES_CpD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n2)),\nsize((n2)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":153582364,"adjusted_p_value":1.0,"path_count":1,"dwpc":3.3841179009927735,"p_value":0.15825413537409552,"reversed":false,"metapath_abbreviation":"CdGuCpD","metapath_name":"Compound–downregulates–Gene–upregulates–Compound–palliates–Disease","metapath_length":3,"metapath_path_count_density":0.029832,"metapath_path_count_mean":0.163171,"metapath_path_count_max":100,"metapath_dwpc_raw_mean":4.82592e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGuCpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Compound","upregulates","both"],["Compound","Disease","palliates","both"]],"dgp_id":23268269,"dgp_source_degree":22,"dgp_target_degree":14,"dgp_n_dwpcs":2400,"dgp_n_nonzero_dwpcs":1201,"dgp_nonzero_mean":2.991566023798353,"dgp_nonzero_sd":1.035278794448917,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:UPREGULATES_CuG]-(n2)-[:PALLIATES_CpD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n2)),\nsize((n2)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":50983018,"adjusted_p_value":1.0,"path_count":25,"dwpc":3.1789727051704726,"p_value":0.16187615509879097,"reversed":false,"metapath_abbreviation":"CuGiGuD","metapath_name":"Compound–upregulates–Gene–interacts–Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0832832,"metapath_path_count_mean":1.66419,"metapath_path_count_max":362,"metapath_dwpc_raw_mean":7.02848e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGiGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Gene","interacts","both"],["Gene","Disease","upregulates","both"]],"dgp_id":24551695,"dgp_source_degree":8,"dgp_target_degree":250,"dgp_n_dwpcs":145800,"dgp_n_nonzero_dwpcs":137268,"dgp_nonzero_mean":2.368401382693425,"dgp_nonzero_sd":0.8894867737327051,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:INTERACTS_GiG]-(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":125134131,"adjusted_p_value":1.0,"path_count":13,"dwpc":3.6743826941725644,"p_value":0.18654460466613315,"reversed":false,"metapath_abbreviation":"CbGiGuD","metapath_name":"Compound–binds–Gene–interacts–Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.12237999999999999,"metapath_path_count_mean":0.633955,"metapath_path_count_max":256,"metapath_dwpc_raw_mean":7.86445e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGiGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","interacts","both"],["Gene","Disease","upregulates","both"]],"dgp_id":21913646,"dgp_source_degree":56,"dgp_target_degree":250,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":5400,"dgp_nonzero_mean":3.2302504766562627,"dgp_nonzero_sd":0.506914377182348,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:INTERACTS_GiG]-(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":38559959,"adjusted_p_value":1.0,"path_count":30,"dwpc":2.8572059585754754,"p_value":0.18927724306716082,"reversed":false,"metapath_abbreviation":"CuG n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":111348878,"adjusted_p_value":1.0,"path_count":17,"dwpc":1.8691182320613013,"p_value":0.19546391364633822,"reversed":false,"metapath_abbreviation":"CuGdAlD","metapath_name":"Compound–upregulates–Gene–downregulates–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.307628,"metapath_path_count_mean":7.848910000000001,"metapath_path_count_max":1010,"metapath_dwpc_raw_mean":0.000102115,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGdAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Anatomy","downregulates","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":24284937,"dgp_source_degree":8,"dgp_target_degree":39,"dgp_n_dwpcs":21600,"dgp_n_nonzero_dwpcs":21058,"dgp_nonzero_mean":1.4147376069386606,"dgp_nonzero_sd":0.5865791641579736,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:DOWNREGULATES_AdG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:DOWNREGULATES_AdG]-()),\nsize(()-[:DOWNREGULATES_AdG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":110948989,"adjusted_p_value":1.0,"path_count":19,"dwpc":2.512300944054508,"p_value":0.19718206577757708,"reversed":false,"metapath_abbreviation":"CbGuAlD","metapath_name":"Compound–binds–Gene–upregulates–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.566498,"metapath_path_count_mean":3.22439,"metapath_path_count_max":358,"metapath_dwpc_raw_mean":0.00012054299999999999,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGuAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Anatomy","upregulates","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":22051850,"dgp_source_degree":56,"dgp_target_degree":39,"dgp_n_dwpcs":800,"dgp_n_nonzero_dwpcs":791,"dgp_nonzero_mean":2.0818765150733842,"dgp_nonzero_sd":0.5315761322514894,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:UPREGULATES_AuG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:UPREGULATES_AuG]-()),\nsize(()-[:UPREGULATES_AuG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":128487525,"adjusted_p_value":1.0,"path_count":13,"dwpc":3.617353906528588,"p_value":0.21161944380965836,"reversed":false,"metapath_abbreviation":"CbGiGdD","metapath_name":"Compound–binds–Gene–interacts–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.12430899999999999,"metapath_path_count_mean":0.605571,"metapath_path_count_max":221,"metapath_dwpc_raw_mean":8.088e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGiGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","interacts","both"],["Gene","Disease","downregulates","both"]],"dgp_id":21847193,"dgp_source_degree":56,"dgp_target_degree":250,"dgp_n_dwpcs":5200,"dgp_n_nonzero_dwpcs":5200,"dgp_nonzero_mean":3.2209791541614377,"dgp_nonzero_sd":0.5092010318492808,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:INTERACTS_GiG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":39335778,"adjusted_p_value":1.0,"path_count":5,"dwpc":3.88546192742891,"p_value":0.2138298621659708,"reversed":false,"metapath_abbreviation":"CtDuGaD","metapath_name":"Compound–treats–Disease–upregulates–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.07452589999999999,"metapath_path_count_mean":0.407038,"metapath_path_count_max":153,"metapath_dwpc_raw_mean":0.000145009,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDuGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","upregulates","both"],["Gene","Disease","associates","both"]],"dgp_id":23825176,"dgp_source_degree":3,"dgp_target_degree":540,"dgp_n_dwpcs":3800,"dgp_n_nonzero_dwpcs":3316,"dgp_nonzero_mean":3.345148180814123,"dgp_nonzero_sd":0.8465984699717739,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:UPREGULATES_DuG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":92028899,"adjusted_p_value":1.0,"path_count":65,"dwpc":1.8071704062278153,"p_value":0.2213157519800908,"reversed":false,"metapath_abbreviation":"CuGeAlD","metapath_name":"Compound–upregulates–Gene–expresses–Anatomy–localizes–Disease","metapath_length":3,"metapath_path_count_density":0.42071899999999995,"metapath_path_count_mean":46.7934,"metapath_path_count_max":4139,"metapath_dwpc_raw_mean":0.000187564,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CuGeAlD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Anatomy","expresses","both"],["Anatomy","Disease","localizes","both"]],"dgp_id":24372263,"dgp_source_degree":8,"dgp_target_degree":39,"dgp_n_dwpcs":21600,"dgp_n_nonzero_dwpcs":21600,"dgp_nonzero_mean":1.523426559007508,"dgp_nonzero_sd":0.39207925987959674,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:EXPRESSES_AeG]-(n2)-[:LOCALIZES_DlA]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:EXPRESSES_AeG]-()),\nsize(()-[:EXPRESSES_AeG]-(n2)),\nsize((n2)-[:LOCALIZES_DlA]-()),\nsize(()-[:LOCALIZES_DlA]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":97068679,"adjusted_p_value":1.0,"path_count":37,"dwpc":2.758675641807037,"p_value":0.24799313274981613,"reversed":false,"metapath_abbreviation":"CuG n2\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":140162570,"adjusted_p_value":1.0,"path_count":98,"dwpc":3.074182176638355,"p_value":0.2541460447587177,"reversed":false,"metapath_abbreviation":"CdG n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":51009514,"adjusted_p_value":1.0,"path_count":1,"dwpc":3.4137832337946725,"p_value":0.25617549219911806,"reversed":false,"metapath_abbreviation":"CbGcGdD","metapath_name":"Compound–binds–Gene–covaries–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.055445299999999996,"metapath_path_count_mean":0.09039900000000001,"metapath_path_count_max":14,"metapath_dwpc_raw_mean":3.7215599999999997e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGcGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","covaries","both"],["Gene","Disease","downregulates","both"]],"dgp_id":21687971,"dgp_source_degree":56,"dgp_target_degree":250,"dgp_n_dwpcs":5200,"dgp_n_nonzero_dwpcs":4835,"dgp_nonzero_mean":2.863715802712182,"dgp_nonzero_sd":1.1049867982806023,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:COVARIES_GcG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:COVARIES_GcG]-()),\nsize(()-[:COVARIES_GcG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":106965472,"adjusted_p_value":1.0,"path_count":138,"dwpc":3.0739067397545172,"p_value":0.26221771349077744,"reversed":false,"metapath_abbreviation":"CdG n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)<-[:REGULATES_GrG]-()),\nsize(()<-[:REGULATES_GrG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":97374812,"adjusted_p_value":1.0,"path_count":4,"dwpc":3.669901367808035,"p_value":0.2823030189749168,"reversed":false,"metapath_abbreviation":"CtDdGaD","metapath_name":"Compound–treats–Disease–downregulates–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.0677816,"metapath_path_count_mean":0.312585,"metapath_path_count_max":105,"metapath_dwpc_raw_mean":0.000126174,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDdGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","downregulates","both"],["Gene","Disease","associates","both"]],"dgp_id":23760232,"dgp_source_degree":3,"dgp_target_degree":540,"dgp_n_dwpcs":3800,"dgp_n_nonzero_dwpcs":3281,"dgp_nonzero_mean":3.338927143537274,"dgp_nonzero_sd":0.8907299516824313,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:DOWNREGULATES_DdG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":118862164,"adjusted_p_value":1.0,"path_count":1,"dwpc":1.0629602031696488,"p_value":0.30267238986391565,"reversed":false,"metapath_abbreviation":"CdGaDrD","metapath_name":"Compound–downregulates–Gene–associates–Disease–resembles–Disease","metapath_length":3,"metapath_path_count_density":0.15983599999999998,"metapath_path_count_mean":1.05379,"metapath_path_count_max":100,"metapath_dwpc_raw_mean":0.00015224,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGaDrD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Disease","associates","both"],["Disease","Disease","resembles","both"]],"dgp_id":22475381,"dgp_source_degree":22,"dgp_target_degree":3,"dgp_n_dwpcs":16800,"dgp_n_nonzero_dwpcs":6475,"dgp_nonzero_mean":1.7436141844499888,"dgp_nonzero_sd":0.833774955434589,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:ASSOCIATES_DaG]-(n2)-[:RESEMBLES_DrD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n2 <> n3\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2)),\nsize((n2)-[:RESEMBLES_DrD]-()),\nsize(()-[:RESEMBLES_DrD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":32420519,"adjusted_p_value":1.0,"path_count":1,"dwpc":2.324917695548423,"p_value":0.3045405147015436,"reversed":false,"metapath_abbreviation":"CuGaD","metapath_name":"Compound–upregulates–Gene–associates–Disease","metapath_length":2,"metapath_path_count_density":0.0649691,"metapath_path_count_mean":0.15582000000000001,"metapath_path_count_max":33,"metapath_dwpc_raw_mean":0.000207821,"metapath_n_similar":13,"metapath_p_threshold":1.0,"metapath_id":"CuGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","upregulates","both"],["Gene","Disease","associates","both"]],"dgp_id":3975327,"dgp_source_degree":8,"dgp_target_degree":540,"dgp_n_dwpcs":5400,"dgp_n_nonzero_dwpcs":2464,"dgp_nonzero_mean":2.7664725888771544,"dgp_nonzero_sd":0.8673842884232502,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:UPREGULATES_CuG]-(n1)-[:ASSOCIATES_DaG]-(n2:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n2.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":39284847,"adjusted_p_value":1.0,"path_count":2,"dwpc":3.222020521239936,"p_value":0.31039008868724677,"reversed":false,"metapath_abbreviation":"CbGuCtD","metapath_name":"Compound–binds–Gene–upregulates–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.0495899,"metapath_path_count_mean":0.11945499999999999,"metapath_path_count_max":78,"metapath_dwpc_raw_mean":6.17764e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGuCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Compound","upregulates","both"],["Compound","Disease","treats","both"]],"dgp_id":22081150,"dgp_source_degree":56,"dgp_target_degree":29,"dgp_n_dwpcs":200,"dgp_n_nonzero_dwpcs":186,"dgp_nonzero_mean":2.870577430113162,"dgp_nonzero_sd":1.1298787882697428,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:UPREGULATES_CuG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:UPREGULATES_CuG]-()),\nsize(()-[:UPREGULATES_CuG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":167156566,"adjusted_p_value":1.0,"path_count":1,"dwpc":3.12813835938026,"p_value":0.32107133973873814,"reversed":false,"metapath_abbreviation":"CdGuD","metapath_name":"Compound–downregulates–Gene–upregulates–Disease","metapath_length":2,"metapath_path_count_density":0.028811400000000004,"metapath_path_count_mean":0.0840122,"metapath_path_count_max":52,"metapath_dwpc_raw_mean":0.000135751,"metapath_n_similar":13,"metapath_p_threshold":1.0,"metapath_id":"CdGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Disease","upregulates","both"]],"dgp_id":3914194,"dgp_source_degree":22,"dgp_target_degree":250,"dgp_n_dwpcs":32400,"dgp_n_nonzero_dwpcs":15572,"dgp_nonzero_mean":3.5167398600218798,"dgp_nonzero_sd":0.7914823800758259,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:UPREGULATES_DuG]-(n2:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n2.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n2))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":47634798,"adjusted_p_value":1.0,"path_count":103,"dwpc":2.917945723916972,"p_value":0.39090323334525856,"reversed":false,"metapath_abbreviation":"CdGiGaD","metapath_name":"Compound–downregulates–Gene–interacts–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.253739,"metapath_path_count_mean":6.4632,"metapath_path_count_max":1289,"metapath_dwpc_raw_mean":0.00012271,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGiGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","interacts","both"],["Gene","Disease","associates","both"]],"dgp_id":22833590,"dgp_source_degree":22,"dgp_target_degree":540,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":1200,"dgp_nonzero_mean":2.82635194827898,"dgp_nonzero_sd":0.39273048786427595,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:INTERACTS_GiG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":42389097,"adjusted_p_value":1.0,"path_count":31,"dwpc":2.965792779701133,"p_value":0.4021955172807161,"reversed":false,"metapath_abbreviation":"CdGr>GdD","metapath_name":"Compound–downregulates–Gene→regulates→Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.11066,"metapath_path_count_mean":3.81032,"metapath_path_count_max":532,"metapath_dwpc_raw_mean":8.182380000000001e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGr>GdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","regulates","forward"],["Gene","Disease","downregulates","both"]],"dgp_id":23086229,"dgp_source_degree":22,"dgp_target_degree":250,"dgp_n_dwpcs":31200,"dgp_n_nonzero_dwpcs":31200,"dgp_nonzero_mean":2.878837938038893,"dgp_nonzero_sd":0.4365387333757429,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:REGULATES_GrG]->(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:REGULATES_GrG]->()),\nsize(()-[:REGULATES_GrG]->(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":44857409,"adjusted_p_value":1.0,"path_count":1,"dwpc":2.626693938487515,"p_value":0.4520702881561719,"reversed":false,"metapath_abbreviation":"CbGcGaD","metapath_name":"Compound–binds–Gene–covaries–Gene–associates–Disease","metapath_length":3,"metapath_path_count_density":0.11458299999999999,"metapath_path_count_mean":0.16275699999999999,"metapath_path_count_max":19,"metapath_dwpc_raw_mean":5.6889300000000004e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGcGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Gene","covaries","both"],["Gene","Disease","associates","both"]],"dgp_id":21669569,"dgp_source_degree":56,"dgp_target_degree":540,"dgp_n_dwpcs":200,"dgp_n_nonzero_dwpcs":199,"dgp_nonzero_mean":2.6332139410418485,"dgp_nonzero_sd":0.9569058517840653,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:COVARIES_GcG]-(n2)-[:ASSOCIATES_DaG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:COVARIES_GcG]-()),\nsize(()-[:COVARIES_GcG]-(n2)),\nsize((n2)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":50633205,"adjusted_p_value":1.0,"path_count":28,"dwpc":2.9747754916204725,"p_value":0.5011721774180102,"reversed":false,"metapath_abbreviation":"CdGiGdD","metapath_name":"Compound–downregulates–Gene–interacts–Gene–downregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0915325,"metapath_path_count_mean":1.99215,"metapath_path_count_max":504,"metapath_dwpc_raw_mean":6.66671e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGiGdD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","interacts","both"],["Gene","Disease","downregulates","both"]],"dgp_id":22865909,"dgp_source_degree":22,"dgp_target_degree":250,"dgp_n_dwpcs":31200,"dgp_n_nonzero_dwpcs":31197,"dgp_nonzero_mean":3.0148882152507985,"dgp_nonzero_sd":0.5894240282429568,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:INTERACTS_GiG]-(n2)-[:DOWNREGULATES_DdG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:DOWNREGULATES_DdG]-()),\nsize(()-[:DOWNREGULATES_DdG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":142009408,"adjusted_p_value":1.0,"path_count":1,"dwpc":3.420518101231946,"p_value":0.5096620686295852,"reversed":false,"metapath_abbreviation":"CtDuGuD","metapath_name":"Compound–treats–Disease–upregulates–Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.033049,"metapath_path_count_mean":0.291745,"metapath_path_count_max":163,"metapath_dwpc_raw_mean":7.55878e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CtDuGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Disease","treats","both"],["Disease","Gene","upregulates","both"],["Gene","Disease","upregulates","both"]],"dgp_id":23856057,"dgp_source_degree":3,"dgp_target_degree":250,"dgp_n_dwpcs":102600,"dgp_n_nonzero_dwpcs":88964,"dgp_nonzero_mean":3.6512621395041713,"dgp_nonzero_sd":0.7986845957034281,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:TREATS_CtD]-(n1)-[:UPREGULATES_DuG]-(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n3\nWITH\n[\nsize((n0)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n1)),\nsize((n1)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":65071150,"adjusted_p_value":1.0,"path_count":1,"dwpc":2.808719698969872,"p_value":0.5194154101338885,"reversed":false,"metapath_abbreviation":"CbGaD","metapath_name":"Compound–binds–Gene–associates–Disease","metapath_length":2,"metapath_path_count_density":0.129327,"metapath_path_count_mean":0.22018200000000002,"metapath_path_count_max":17,"metapath_dwpc_raw_mean":0.000492032,"metapath_n_similar":13,"metapath_p_threshold":1.0,"metapath_id":"CbGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Disease","associates","both"]],"dgp_id":3546793,"dgp_source_degree":56,"dgp_target_degree":540,"dgp_n_dwpcs":200,"dgp_n_nonzero_dwpcs":200,"dgp_nonzero_mean":2.8799611669781537,"dgp_nonzero_sd":0.6043977102968453,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:ASSOCIATES_DaG]-(n2:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n2.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":68245162,"adjusted_p_value":1.0,"path_count":627,"dwpc":2.642584893576034,"p_value":0.5233118308199263,"reversed":false,"metapath_abbreviation":"CcSEcCpD","metapath_name":"Compound–causes–Side Effect–causes–Compound–palliates–Disease","metapath_length":3,"metapath_path_count_density":0.24537199999999998,"metapath_path_count_mean":85.6848,"metapath_path_count_max":5401,"metapath_dwpc_raw_mean":0.000400305,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CcSEcCpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Side Effect","causes","both"],["Side Effect","Compound","causes","both"],["Compound","Disease","palliates","both"]],"dgp_id":22258796,"dgp_source_degree":139,"dgp_target_degree":14,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":1200,"dgp_nonzero_mean":2.654568073101843,"dgp_nonzero_sd":0.1541842558927804,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:CAUSES_CcSE]-(n1)-[:CAUSES_CcSE]-(n2)-[:PALLIATES_CpD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:CAUSES_CcSE]-()),\nsize(()-[:CAUSES_CcSE]-(n1)),\nsize((n1)-[:CAUSES_CcSE]-()),\nsize(()-[:CAUSES_CcSE]-(n2)),\nsize((n2)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":97095112,"adjusted_p_value":1.0,"path_count":1,"dwpc":2.107733492156172,"p_value":0.5498069779901729,"reversed":false,"metapath_abbreviation":"CdGaD","metapath_name":"Compound–downregulates–Gene–associates–Disease","metapath_length":2,"metapath_path_count_density":0.0543965,"metapath_path_count_mean":0.129247,"metapath_path_count_max":62,"metapath_dwpc_raw_mean":0.000168682,"metapath_n_similar":13,"metapath_p_threshold":1.0,"metapath_id":"CdGaD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Disease","associates","both"]],"dgp_id":3764605,"dgp_source_degree":22,"dgp_target_degree":540,"dgp_n_dwpcs":1200,"dgp_n_nonzero_dwpcs":826,"dgp_nonzero_mean":2.8313251950826324,"dgp_nonzero_sd":0.847768764664304,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:ASSOCIATES_DaG]-(n2:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n2.identifier = 'DOID:1612' // breast cancer\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:ASSOCIATES_DaG]-()),\nsize(()-[:ASSOCIATES_DaG]-(n2))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":48854515,"adjusted_p_value":1.0,"path_count":27,"dwpc":2.8601539373754448,"p_value":0.5681367868494877,"reversed":false,"metapath_abbreviation":"CdGiGuD","metapath_name":"Compound–downregulates–Gene–interacts–Gene–upregulates–Disease","metapath_length":3,"metapath_path_count_density":0.0933385,"metapath_path_count_mean":2.29914,"metapath_path_count_max":664,"metapath_dwpc_raw_mean":6.89717e-05,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CdGiGuD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","downregulates","both"],["Gene","Gene","interacts","both"],["Gene","Disease","upregulates","both"]],"dgp_id":22983179,"dgp_source_degree":22,"dgp_target_degree":250,"dgp_n_dwpcs":32400,"dgp_n_nonzero_dwpcs":32399,"dgp_nonzero_mean":2.9937325587204735,"dgp_nonzero_sd":0.5747370000868853,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:DOWNREGULATES_CdG]-(n1)-[:INTERACTS_GiG]-(n2)-[:UPREGULATES_DuG]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n1 <> n2\nWITH\n[\nsize((n0)-[:DOWNREGULATES_CdG]-()),\nsize(()-[:DOWNREGULATES_CdG]-(n1)),\nsize((n1)-[:INTERACTS_GiG]-()),\nsize(()-[:INTERACTS_GiG]-(n2)),\nsize((n2)-[:UPREGULATES_DuG]-()),\nsize(()-[:UPREGULATES_DuG]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":108601103,"adjusted_p_value":1.0,"path_count":1367,"dwpc":2.2363318477976017,"p_value":0.9898650141772094,"reversed":false,"metapath_abbreviation":"CcSEcCtD","metapath_name":"Compound–causes–Side Effect–causes–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.38648000000000005,"metapath_path_count_mean":139.04399999999998,"metapath_path_count_max":6460,"metapath_dwpc_raw_mean":0.0005849609999999999,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CcSEcCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Side Effect","causes","both"],["Side Effect","Compound","causes","both"],["Compound","Disease","treats","both"]],"dgp_id":22266292,"dgp_source_degree":139,"dgp_target_degree":29,"dgp_n_dwpcs":600,"dgp_n_nonzero_dwpcs":600,"dgp_nonzero_mean":2.482680921586012,"dgp_nonzero_sd":0.10915828891309523,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:CAUSES_CcSE]-(n1)-[:CAUSES_CcSE]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:CAUSES_CcSE]-()),\nsize(()-[:CAUSES_CcSE]-(n1)),\nsize((n1)-[:CAUSES_CcSE]-()),\nsize(()-[:CAUSES_CcSE]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":68766558,"adjusted_p_value":1.0,"path_count":7,"dwpc":2.1435211643467356,"p_value":0.9995290849496753,"reversed":false,"metapath_abbreviation":"CbGbCtD","metapath_name":"Compound–binds–Gene–binds–Compound–treats–Disease","metapath_length":3,"metapath_path_count_density":0.283896,"metapath_path_count_mean":3.38381,"metapath_path_count_max":215,"metapath_dwpc_raw_mean":0.000546079,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGbCtD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Compound","binds","both"],["Compound","Disease","treats","both"]],"dgp_id":21649384,"dgp_source_degree":56,"dgp_target_degree":29,"dgp_n_dwpcs":200,"dgp_n_nonzero_dwpcs":200,"dgp_nonzero_mean":3.0123063100018,"dgp_nonzero_sd":0.2903843172307362,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:BINDS_CbG]-(n2)-[:TREATS_CtD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n2)),\nsize((n2)-[:TREATS_CtD]-()),\nsize(()-[:TREATS_CtD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"},{"id":100427380,"adjusted_p_value":1.0,"path_count":5,"dwpc":1.4124432500181578,"p_value":0.999999999785775,"reversed":false,"metapath_abbreviation":"CbGbCpD","metapath_name":"Compound–binds–Gene–binds–Compound–palliates–Disease","metapath_length":3,"metapath_path_count_density":0.186823,"metapath_path_count_mean":2.5267,"metapath_path_count_max":359,"metapath_dwpc_raw_mean":0.00041236,"metapath_n_similar":121,"metapath_p_threshold":1.0,"metapath_id":"CbGbCpD","metapath_reversed":false,"metapath_metaedges":[["Compound","Gene","binds","both"],["Gene","Compound","binds","both"],["Compound","Disease","palliates","both"]],"dgp_id":21648119,"dgp_source_degree":56,"dgp_target_degree":14,"dgp_n_dwpcs":400,"dgp_n_nonzero_dwpcs":400,"dgp_nonzero_mean":3.1124787212818323,"dgp_nonzero_sd":0.3460175642057741,"dgp_reversed":false,"cypher_query":"MATCH path = (n0:Compound)-[:BINDS_CbG]-(n1)-[:BINDS_CbG]-(n2)-[:PALLIATES_CpD]-(n3:Disease)\nUSING JOIN ON n1\nWHERE n0.identifier = 'DB00331' // Metformin\nAND n3.identifier = 'DOID:1612' // breast cancer\nAND n0 <> n2\nWITH\n[\nsize((n0)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n1)),\nsize((n1)-[:BINDS_CbG]-()),\nsize(()-[:BINDS_CbG]-(n2)),\nsize((n2)-[:PALLIATES_CpD]-()),\nsize(()-[:PALLIATES_CpD]-(n3))\n] AS degrees, path\nWITH path, reduce(pdp = 1.0, d in degrees| pdp * d ^ -0.5) AS PDP\nWITH collect({paths: path, PDPs: PDP}) AS data_maps, count(path) AS PC, sum(PDP) AS DWPC\nUNWIND data_maps AS data_map\nWITH data_map.paths AS path, data_map.PDPs AS PDP, PC, DWPC\nRETURN\n path AS neo4j_path,\n substring(reduce(s = '', node IN nodes(path)| s + '–' + node.name), 1) AS path,\n PDP,\n 100 * (PDP / DWPC) AS percent_of_DWPC\nORDER BY percent_of_DWPC DESC\nLIMIT 10"}]}